Sequence-Dependent Effects on the Properties of Semiflexible Biopolymers

Using path integral technique, we show exactly that for a semiflexible biopolymer in constant extension ensemble, no matter how long the polymer and how large the external force, the effects of short range correlations in the sequence-dependent spontaneous curvatures and torsions can be incorporated into a model with well-defined mean spontaneous curvature and torsion as well as a renormalized persistence length. Moreover, for a long biopolymer with large mean persistence length, the sequence-dependent persistence lengths can be replaced by their mean. However, for a short biopolymer or for a biopolymer with small persistence lengths, inhomogeneity in persistence lengths tends to make physical observables very sensitive to details and therefore less predictable

Disordered, stretched, and semiflexible biopolymers in two dimensions

We study the effects of intrinsic sequence-dependent curvature for a two dimensional semiflexible biopolymer with short-range correlation in intrinsic curvatures. We show exactly that when not subjected to any external force, such a system is equivalent to a system with a well-defined intrinsic curvature and a proper renormalized persistence length. We find the exact expression for the distribution function of the equivalent system. However, we show that such an equivalent system does not always exist for the polymer subjected to an external force. We find that under an external force, the effect of sequence-disorder depends upon the averaging order, the degree of disorder, and the experimental conditions, such as the boundary conditions. Furthermore, a short to moderate length biopolymer may be much softer or has a smaller apparent persistent length than what would be expected from the "equivalent system". Moreover, under a strong stretching force and for a long biopolymer, the sequence-disorder is immaterial for elasticity. Finally, the effect of sequence-disorder may depend upon the quantity considered

On the Hamiltonian structure of Ermakov systems

A canonical Hamiltonian formalism is derived for a class of Ermakov systems specified by several different frequency functions. This class of systems comprises all known cases of Hamiltonian Ermakov systems and can always be reduced to quadratures. The Hamiltonian structure is explored to find exact solutions for the Calogero system and for a noncentral potential with dynamic symmetry. Some generalizations of these systems possessing exact solutions are also identified and solved

Heisenberg-picture approach to the exact quantum motion of a time-dependent forced harmonic oscillator

In the Heisenberg picture, the generalized invariant and exact quantum motions are found for a time-dependent forced harmonic oscillator. We find the eigenstate and the coherent state of the invariant and show that the dispersions of these quantum states do not depend on the external force. Our formalism is applied to several interesting cases.Comment: 15 pages, two eps files, to appear in Phys. Rev. A 53 (6) (1996

Green's function for the Relativistic Coulomb System via Sum Over Perturbation Series

We evaluate the Green's function of the D-dimensional relativistic Coulomb system via sum over perturbation series which is obtained by expanding the exponential containing the potential term $V({\bf x)}$ in the path integral into a power series. The energy spectra and wave functions are extracted from the resulting amplitude.Comment: 13 pages, ReVTeX, no figure

Complex Effective Path: A Semi-Classical Probe of Quantum Effects

We discuss the notion of an effective, average, quantum mechanical path which is a solution of the dynamical equations obtained by extremizing the quantum effective action. Since the effective action can, in general, be complex, the effective path will also, in general, be complex. The imaginary part of the effective action is known to be related to the probability of particle creation by an external source and hence we expect the imaginary part of the effective path also to contain information about particle creation. We try to identify such features using simple examples including that of effective path through the black hole horizon leading to thermal radiation. Implications of this approach are discussed.Comment: 20 pages; no figures; to appear in Phys.Rev.

Brownian Motion and Polymer Statistics on Certain Curved Manifolds

We have calculated the probability distribution function G(R,L|R',0) of the end-to-end vector R-R' and the mean-square end-to-end distance (R-R')^2 of a Gaussian polymer chain embedded on a sphere S^(D-1) in D dimensions and on a cylinder, a cone and a curved torus in 3-D. We showed that: surface curvature induces a geometrical localization area; at short length the polymer is locally "flat" and (R-R')^2 = L l in all cases; at large scales, (R-R')^2 is constant for the sphere, it is linear in L for the cylinder and reaches different constant values for the torus. The cone vertex induces (function of opening angle and R') contraction of the chain for all lengths. Explicit crossover formulas are derived.Comment: 9 pages, 4 figures, RevTex, uses amssymb.sty and multicol.sty, to appear in Phys. Rev

Free energy of the Fr\"ohlich polaron in two and three dimensions

We present a novel Path Integral Monte Carlo scheme to solve the Fr\"ohlich polaron model. At intermediate and strong electron-phonon coupling, the polaron self-trapping is properly taken into account at the level of an effective action obtained by a preaveraging procedure with a retarded trial action. We compute the free energy at several couplings and temperatures in three and two dimensions. Our results show that the accuracy of the Feynman variational upper bound for the free energy is always better than 5% although the thermodynamics derived from it is not correct. Our estimates of the ground state energies demonstrate that the second cumulant correction to the variational upper bound predicts the self energy to better than 1% at intermediate and strong coupling.Comment: RevTeX 7 pages 3 figures, revised versio

Estimating Temperature Fluctuations in the Early Universe

A lagrangian for the $k-$ essence field is constructed for a constant scalar potential and its form determined when the scale factor was very small compared to the present epoch but very large compared to the inflationary epoch. This means that one is already in an expanding and flat universe. The form is similar to that of an oscillator with time-dependent frequency. Expansion is naturally built into the theory with the existence of growing classical solutions of the scale factor. The formalism allows one to estimate fluctuations of the temperature of the background radiation in these early stages (compared to the present epoch) of the universe. If the temperature at time $t_{a}$ is $T_{a}$ and at time $t_{b}$ the temperature is $T_{b}$ ($t_{b}>t_{a}$), then for small times, the probability for the logarithm of inverse temperature evolution can be estimated to be given by $$P(b,a)= |\langle ln~({1\over T_{b}}),t_{b}| ln~({1\over T_{a}}),t_{a}\rangle|^{2}$$ $$\approx\biggl({3m_{\mathrm Pl}^{2}\over \pi^{2} (t_{b}-t_{a})^{3}}\biggr) (ln~ T_{a})^{2}(ln~T_{b})^{2}\biggl(1 - 3\gamma (t_{a} + t_{b})\biggr)$$ where $0<\gamma<1$, $m_{\mathrm Pl}$ is the Planck mass and Planck's constant and the speed of light has been put equal to unity. There is the further possibility that a single scalar field may suffice for an inflationary scenario as well as the dark matter and dark energy realms.Comment: 8 pages, Revtex, title,abstract and format changed for journal publication,no change in basic results, clarifications and a figure added. Keywords: physics of the early universe,inflation, dark matter theory, dark energy theory. PACS: 95.35.+d ; 95.36.+x ; 98.80.Cq ; 98.80.-